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Dose finding by the continual reassessment method / Ying Kuen Cheung.

By: Series: Chapman & Hall/CRC biostatistics series ; 41.Publication details: Boca Raton : CRC Press, c2011.Description: xv, 189 p. : ill. ; 25 cmISBN:
  • 9781420091519 (hbk.)
  • 1420091514 (hbk.)
Subject(s): DDC classification:
  • 615.1 CHE 2011
Contents:
Dose finding in clinical trials -- The continual reassessment method -- One-parameter dose toxicity models -- Theoretical properties -- Empirical properties -- Specifications of a CRM design -- Initial guesses of toxicity probabilities -- Least informative normal prior -- Initial design -- The time-to-event CRM -- CRM with multiparameter models -- When the CRM fails -- Stochastic approximation.
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Cover image Item type Current library Home library Collection Shelving location Shelf location Call number Materials specified Vol info Copy number Status Notes Date due Barcode Item holds Item hold queue priority Course reserves
Main Collection Taylor's Library-TU 615.1 CHE 2011 (Browse shelf(Opens below)) 1 Available SOPxx,31001,03,CL 5000128421

Includes bibliographical references and index.

Dose finding in clinical trials -- The continual reassessment method -- One-parameter dose toxicity models -- Theoretical properties -- Empirical properties -- Specifications of a CRM design -- Initial guesses of toxicity probabilities -- Least informative normal prior -- Initial design -- The time-to-event CRM -- CRM with multiparameter models -- When the CRM fails -- Stochastic approximation.