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Nutritional genomics : impact on health and disease / edited by Regina Brigelius-Flohé, Hans-Georg Joost.

Contributor(s): Publication details: Weinheim : Wiley-VCH, c2006.Description: xxviii, 442 p. : ill. ; 25 cmISBN:
  • 3527312943 (hbk.)
  • 9783527312948 (hbk.)
Subject(s): DDC classification:
  • 612.3 NUT
Contents:
Foreword. - Preface. - Contributors. - List of abbreviations. - Part I: Introduction - Definitions. - 1. Nutritional genomics: concepts, tools and expectations. - Part II: Nutrigenomics (Nutrient-gene interactions). - 2. Nuclear receptors: an overview. - 3. Mechanism of action and cancer therapeutic potential of retinoids. - 4. Nuclear receptors and the control of gene expression by fatty acids. - 5. Cellular adaptation to amino acid availability : mechanism involved in the regulation of gene expression. - 6. Transcriptional regulation of hepatic genes by insulin and glucose. - 7. PPARs: Lipid sensors that regulate cell differentiation processes. - 8. Advances in Selenoprotein expression: patterns and individual variations. - 9. PPARs in Atherosclerosis. - 10. Protein synthesis and cancer. - 11. Mutations in the PPARy gene relevent for diabetes and the metabolic syndrome. - 12. Regulation of Lipogenic genes in obesity. - Part III: Nutrigenetics (nutrient-genotype interactions). - 13. The genetics of type 2 diabetes. - 14. Gene variants of obesity. - 15. Gene polymorphisms, nutrition, and the inflammatory response. - 16. Gene variants, nutritional parameters, and hypertension. - 17. Gene variants, nutrition, and cancer. - 18. Taste receptors and their variants. - 10. Cancer and gene variants in enzymes metabolizing dietry xenobiotics. - Index.
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Includes bibliographical references and index.

Foreword. - Preface. - Contributors. - List of abbreviations. - Part I: Introduction - Definitions. - 1. Nutritional genomics: concepts, tools and expectations. - Part II: Nutrigenomics (Nutrient-gene interactions). - 2. Nuclear receptors: an overview. - 3. Mechanism of action and cancer therapeutic potential of retinoids. - 4. Nuclear receptors and the control of gene expression by fatty acids. - 5. Cellular adaptation to amino acid availability : mechanism involved in the regulation of gene expression. - 6. Transcriptional regulation of hepatic genes by insulin and glucose. - 7. PPARs: Lipid sensors that regulate cell differentiation processes. - 8. Advances in Selenoprotein expression: patterns and individual variations. - 9. PPARs in Atherosclerosis. - 10. Protein synthesis and cancer. - 11. Mutations in the PPARy gene relevent for diabetes and the metabolic syndrome. - 12. Regulation of Lipogenic genes in obesity. - Part III: Nutrigenetics (nutrient-genotype interactions). - 13. The genetics of type 2 diabetes. - 14. Gene variants of obesity. - 15. Gene polymorphisms, nutrition, and the inflammatory response. - 16. Gene variants, nutritional parameters, and hypertension. - 17. Gene variants, nutrition, and cancer. - 18. Taste receptors and their variants. - 10. Cancer and gene variants in enzymes metabolizing dietry xenobiotics. - Index.