Prazeres, Duarte Miguel F.
Plasmid biopharmaceuticals : basics, applications, and manufacturing / Duarte Miguel F. Prazeres. - Hoboken, N.J. : John Wiley, c2011. - xix, 590 p. : ill. ; 25 cm.
Includes bibliographical references and index.
Historical perspective -- Gene transfer with plasmid biopharmaceuticals -- Product and process development -- Structure -- Analytical characterization -- Delivery -- Ethical and safety issues -- Human and veterinary markets -- Human case studies : pandemic influenza and critical limb ischaemia -- Veterinary case studies : West Nile, infectious hematopoietic necrosis, and melanoma -- GMPS and validation -- Product specifications and quality control -- Cell culture -- An overview of downstream processing -- Primary isolation -- Intermediate recovery -- Final purification -- Process synthesis -- Concluding remarks and outlook.
9780470232927 (hbk.) 9780470939918 (obk.) 9780470939871 (ePDF) 9781118002254 (ePub)
Plasmids.
Biopharmaceutics.
615.1 / PRA 2011
Plasmid biopharmaceuticals : basics, applications, and manufacturing / Duarte Miguel F. Prazeres. - Hoboken, N.J. : John Wiley, c2011. - xix, 590 p. : ill. ; 25 cm.
Includes bibliographical references and index.
Historical perspective -- Gene transfer with plasmid biopharmaceuticals -- Product and process development -- Structure -- Analytical characterization -- Delivery -- Ethical and safety issues -- Human and veterinary markets -- Human case studies : pandemic influenza and critical limb ischaemia -- Veterinary case studies : West Nile, infectious hematopoietic necrosis, and melanoma -- GMPS and validation -- Product specifications and quality control -- Cell culture -- An overview of downstream processing -- Primary isolation -- Intermediate recovery -- Final purification -- Process synthesis -- Concluding remarks and outlook.
9780470232927 (hbk.) 9780470939918 (obk.) 9780470939871 (ePDF) 9781118002254 (ePub)
Plasmids.
Biopharmaceutics.
615.1 / PRA 2011