Biomedical applications of proteomics / edited by Jean-Charles Sanchez, Garry L. Corthals, Denis F. Hochstrasser. - Weinheim : Wiley-VCH, c2004. - xxvii, 435 p. : ill. (some col.) ; 25 cm.

Includes bibliographical references and index.

List of contributors. - Abbreviations. - Introduction. - Part 1: Aspects in biomedical research.1. Proteomics in biomedicine - a tool, a science, or an art? - Part II: Blood vessels. - 2. Antibody-based vascular targeting: proteomic techniques for the identification and quantification of membrane proteins on endothelial cells. - 3. Vasculature, vascular disease and atherosclerosis. - 4. Discovery of new diagnostic markers of stroke. - Part III: Cancer. - 5. Unravelling biological pathways and the identification of clinical markers and targets in renal cancer. - 6. Heat shock protein 27 in cancer. - 7. Proteomic Approaches for biomarker discovery in colorectal cancer. - 8. Clinical proteomics: ovarian cancer. - 9. Protein expression profiling analysis in hematopoietic stem cells: Phenotypic characterization of mesenchymal stem cells. - 10. Lymphoblastoid and lymphoma cells. - Part IV: Pharmaco-toxicology. - 11. Chemoresistance in cancer cells. - 12. Diabetes mellitus: complex molecular alterations. - Par V: Infectious diseases. - 13. Proteome approach to infectious diseases: acute-phase proteins and antibody profiles as diagnostic indicators in human plasma. - 14. Proteomic studies of human lymphocytes: new insights into HIV lymphocyte infection? . - 15. Modifications of host cell proteomes induced by herpes simplex virus type 1. - 16. Francisella tularensis. - Part VI: Central nervous system. - 17. Proteomics in clinical neurosciences. - 18. Human cerebrospinal fluid. - 19. Proteomic applications for molecular assessment of Alzheimer's Disease. - Part VII: Mass spectrometry and bioinformatics. - 21. Protein variations: resources and tools. - Subject index.

3527308075 (hbk.)


Pathology, Molecular.
Proteomics.
Biochemical markers.
Proteins--Therapeutic use.

616.07 / BIO