Immunogenomics and human disease /
[edited by] András Falus.
- Chichester, West Sussex, England : John Wiley, c2006.
- xxi, 526 p. : ill. (some col.) ; 26 cm.
Includes bibliographical references and index.
Preface. - List of contributors. - 1. Genotyping methods and disease gene identification. - 2. Glycomics and the sugar code: primer to their structural basis and functionality. - 3. Proteomics in clinical research: perspectives and expectations. - 4. Chemical genomics: bridging the gap between novel targets and small molecule drug candidates. Contribution to immunology. - 5. Genomic and proteomic analysis of activated human monocytes. - 6. Bioinformatics as a problem of knowlege representation: applications to some aspects of immunoregulation. - 7. Immune responsiveness of human tumours. - 8. Chemokines regulate leukocyte trafficking and organ-specific metastasis. - 9. Towards a unified approach to new target discovery in breast cancer: combining the power of genomics, proteomics and immunology. - 10. Genomics and functional differences of dendritic cell subsets. - 11. Systemic lupus erythematosus: new ideas for diagnosis and treatment. - 12. Immunogenetics of experimentally induced arthritis. - 13. Synovial activation in rheumatoid arthiritis. - 14. T cell epitope hierarchy in experimental autoimmune models. - 15. Gene-gene interaction in immunology as exemplified by studies on autoantibodies against 60 kDa heat-shock protein. - 16. Histamine genomics and metabolomics. - 17. The histamine H4 receptor: drug discovery in the post-genomic era. - 18. Application of microarray technology to bronchial asthma. - 19. Genomic investigation of asthma in human and animal models. - 20. Primary immunodeficiencies: genotype-phenotype correlations. - 21. Transcriptional profiling of dentritic cells in response to pathogens. - 22. Parallel biology: a systematic approach to drug target and biomarker discovery in chronic obstructive pulmonary disease. - 23. Mycobacterial granulomas: a genomic approach. - Index.
0470015306 (hbk.)
Immunogenetics.
616.0796 / IMU
Includes bibliographical references and index.
Preface. - List of contributors. - 1. Genotyping methods and disease gene identification. - 2. Glycomics and the sugar code: primer to their structural basis and functionality. - 3. Proteomics in clinical research: perspectives and expectations. - 4. Chemical genomics: bridging the gap between novel targets and small molecule drug candidates. Contribution to immunology. - 5. Genomic and proteomic analysis of activated human monocytes. - 6. Bioinformatics as a problem of knowlege representation: applications to some aspects of immunoregulation. - 7. Immune responsiveness of human tumours. - 8. Chemokines regulate leukocyte trafficking and organ-specific metastasis. - 9. Towards a unified approach to new target discovery in breast cancer: combining the power of genomics, proteomics and immunology. - 10. Genomics and functional differences of dendritic cell subsets. - 11. Systemic lupus erythematosus: new ideas for diagnosis and treatment. - 12. Immunogenetics of experimentally induced arthritis. - 13. Synovial activation in rheumatoid arthiritis. - 14. T cell epitope hierarchy in experimental autoimmune models. - 15. Gene-gene interaction in immunology as exemplified by studies on autoantibodies against 60 kDa heat-shock protein. - 16. Histamine genomics and metabolomics. - 17. The histamine H4 receptor: drug discovery in the post-genomic era. - 18. Application of microarray technology to bronchial asthma. - 19. Genomic investigation of asthma in human and animal models. - 20. Primary immunodeficiencies: genotype-phenotype correlations. - 21. Transcriptional profiling of dentritic cells in response to pathogens. - 22. Parallel biology: a systematic approach to drug target and biomarker discovery in chronic obstructive pulmonary disease. - 23. Mycobacterial granulomas: a genomic approach. - Index.
0470015306 (hbk.)
Immunogenetics.
616.0796 / IMU