000 -LEADER |
fixed length control field |
02292nam a2200265 a 4500 |
001 - CONTROL NUMBER |
control field |
vtls003042817 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
MY-SjTCS |
005 - DATE AND TIME OF LATEST TRANSACTION |
control field |
20200306165938.0 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
110218s2005 gw a b 001 0 eng d |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
International Standard Book Number |
9783527308194 |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
International Standard Book Number |
3527308199 (hbk.) |
039 #9 - LEVEL OF BIBLIOGRAPHIC CONTROL AND CODING DETAIL [OBSOLETE] |
Level of rules in bibliographic description |
201102181616 |
Level of effort used to assign nonsubject heading access points |
VLOAD |
Level of effort used to assign subject headings |
200704130950 |
Level of effort used to assign classification |
Irma |
Level of effort used to assign subject headings |
200704041241 |
Level of effort used to assign classification |
radtha |
Level of effort used to assign subject headings |
200704041241 |
Level of effort used to assign classification |
radtha |
-- |
200703261722 |
-- |
jamalia |
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
Classification number |
615.7 |
Item number |
GPCR |
245 00 - TITLE STATEMENT |
Title |
G protein-coupled receptors as drug targets : |
Remainder of title |
analysis of activation and constitutive activity / |
Statement of responsibility, etc. |
edited by Roland Seifert and Thomas Wieland. |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Place of publication, distribution, etc. |
Weinheim : |
Name of publisher, distributor, etc. |
Wiley-VCH, |
Date of publication, distribution, etc. |
c2005. |
300 ## - PHYSICAL DESCRIPTION |
Extent |
xxvii, 275 p. |
Other physical details |
ill. |
Dimensions |
26 cm. |
440 #0 - SERIES STATEMENT/ADDED ENTRY--TITLE |
Title |
Methods and principles in medicinal chemistry ; |
Volume/sequential designation |
v. 24 |
9 (RLIN) |
24055 |
504 ## - BIBLIOGRAPHY, ETC. NOTE |
Bibliography, etc. note |
Includes bibliographical references and index. |
505 0# - FORMATTED CONTENTS NOTE |
Formatted contents note |
Preface. - A personal foreword. - List of contributors. - Abbreviations and terminology. - I. General concepts. - 1. Historical background and introduction. - 2. The nature of constitutive activity and inverse agonism. - 3. Molecular mechanisms of GPCR activation. - 4. Molecular and cellular determinants of GPCR splice variant constitutive activity. - 5. Naturally occurring constitutively active receptors: physiologic and pharmacologic implications. - 6. The impact of G-Proteins on constitutive GPCR activity. - 7. (Patho)physiological and therapeutic relevance of constitutive GPCR activity and inverse agonism at GProtein-coupled receptors. - 8. Methodological approaches. - II. Constitutive activity of selected GPCR systems. - 9. Constitutive activity of -adrenoceptors: analysis in membrane systems. - 10. Constitutive activity of -adrenoceptors: analysis by physiological methods. - 11. Constitutive activity at the 1-Adrenoceptors: past and future implications. - 12. Constitutive activity of muscarinic acetylcholine receptors: implications for receptor activation and physiological relevance. - 13.Constitutively active histamine receptors.- 14. Constitutively active serotonin receptors. - 15. Virally encoded constitutively active chemokine receptors. - Index. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
G proteins. |
9 (RLIN) |
24056 |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Drug targeting. |
9 (RLIN) |
24058 |
700 1# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Seifert, Roland. |
Relator term |
(ed.) |
9 (RLIN) |
275773 |
700 1# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Wieland, Thomas, |
Dates associated with a name |
1960- |
Relator term |
(j.ed.) |
9 (RLIN) |
275774 |
920 ## - Programme |
Programme |
BMS : 261005 |
999 ## - SYSTEM CONTROL NUMBERS (KOHA) |
Koha biblionumber |
59168 |
Koha biblioitemnumber |
59168 |