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Biotransformation and metabolite elucidation of xenobiotics / edited by Ala F. Nassar.

Contributor(s): Nassar, Ala F.
Publisher: Hoboken, N.J. : John Wiley, c2010Description: xi, 328 p. : ill. ; 25 cm.ISBN: 9780470504789 (hbk.); 0470504781 (hbk.).Subject(s): Xenobiotics -- Metabolism | Metabolites -- Identification | Biotransformation (Metabolism)DDC classification: 615.9
Contents:
Human biotransformation / Andrew Parkinson -- Analytical tools and approaches for metabolite identification in drug metabolism / Yongmei Li -- Tools of choice for accelerating metabolite identification : mass spec technology drives metabolite identification studies forward / Ala Nassar -- Improving drug design : considerations for the structural modification process / Ala Nassar -- Case study : the unanticipated loss of N2 from novel dna alkylating agent laromustine by collision-induced dissociation : novel rearrangements / Ala Nassar, Tukiet T. Lam -- Case study : identification of in vitro metabolite/decomposition products of the novel DNA alkylating agent laromustine / Ala Nassar, TuKiet T. Lam -- Strategies for the detection of reactive intermediates in drug discovery and development / Mark P. Grillo -- Safety testing of drug metabolites : MIST guidance impact on the practice of industrial drug metabolism / J. Greg Slatter.
Item type Current location Call number Copy number Status Notes Date due Barcode Remark
Main Collection TU External Storage-LCS
615.9 BIO 2010 (Browse shelf) 1 Available SOPxx,31001,03,CL 5000128519 Please fill up online form at https://taylorslibrary.taylors.edu.my/services/external_storage1

"Characterization and identification"--Cover.

Includes bibliographical references and index.

Human biotransformation / Andrew Parkinson -- Analytical tools and approaches for metabolite identification in drug metabolism / Yongmei Li -- Tools of choice for accelerating metabolite identification : mass spec technology drives metabolite identification studies forward / Ala Nassar -- Improving drug design : considerations for the structural modification process / Ala Nassar -- Case study : the unanticipated loss of N2 from novel dna alkylating agent laromustine by collision-induced dissociation : novel rearrangements / Ala Nassar, Tukiet T. Lam -- Case study : identification of in vitro metabolite/decomposition products of the novel DNA alkylating agent laromustine / Ala Nassar, TuKiet T. Lam -- Strategies for the detection of reactive intermediates in drug discovery and development / Mark P. Grillo -- Safety testing of drug metabolites : MIST guidance impact on the practice of industrial drug metabolism / J. Greg Slatter.