Contents:List of contributors. - Preface. - Ch. 1. Molecular mechanisms regulating actin filament dynamics at the leading edge of motile cells (Thomas D. Pollard). - Ch. 2. The Role of Talin and Myosin VII in Adhesion - A FERM Connection (Margaret A. Titus). - Ch. 3. Do class I myosins exert their functions through regulation of actin dynamics? (Thierry Soldati and Claudia Kistler). - Ch. 4. Ephrin regulated contact repulsion of growth cones (Lene K. Harbott, Daniel J. Marston and Catherine D. Nobes). - Ch. 5. Interplay between the actin cytoskeleton, focal adhesions, and microtubules (Christoph Ballestrem, Natalia Magid, Julia Zonis, Michael Shtutman, and Alexander Bershadsky). - Ch. 6. Initial Steps from cell migration to cell-cell adhesion (Jason S. Ehrlich,W. James Nelson and Marc D. H. Hansen). - Ch. 7. Using bioprobes to follow protein dynamics in living cells (Mark R. Holt, Daniel Y.H. Soong, James Monypenny, Ian M. Dobbie, Daniel Zicha and Graham A. Dunn). - Ch. 8. Actin Filament Assembly: The Search for a Barbed End (Craig F. Stovold, Stewart J. Sharp and Laura M. Machesky). - Ch. 9. Role of WASP family proteins in cytoskeletal reorganization and cell motility (Tadaomi Takenawa and Shiro Suetsugu). - Ch. 10. Regulation and function of the small GTP-binding protein ARF6 in membrane dynamics (Thierry Dubois, Emma Colucci-Guyon, Florence Niedergang, Magali Prigent and Philippe Chavrier). - Ch. 11. Chemotaxis of cancer cells during invasion and metastasis (John Condeelis, Xiaoyan Song, Jonathan M. Backer, Jeffrey Wyckoff and Jeffrey Segall). - Ch. 12. Dynamin and cytoskeletal-dependent membrane processes (James D. Orth, Noah W. Gray, Heather M. Thompson and Mark A. McNiven). - Ch. 13. Regulation of microtubule dynamics in migrating cells: a new role for Rho GTPases (Torsten Wittmann and Clare M. Waterman-Storer). - Ch. 14. Calpain regulation of cell migration (Anna Huttenlocher). - Ch. 15. Role of villin in the dynamics of actin microfilaments (Rafika Athman, Sylvie Robine and Daniel Louvard). - Ch. 16. Scar, WASP and the Arp2/3 complex in dictyostelium migration (Simone Blagg and Robert Insall). - Ch. 17. Directional sensing: subcellular targeting of GPCR downstream effectors during chemotaxis (Satoru Funamoto and Richard A. Firtel). - Ch. 18. Cell crawling, cell behavior and biomechanics during convergence and extension (Ray Keller and Lance Davidson). - Ch. 19. Regulation of cell migration in vitro and in vivo (Donna J. Webb, Karen Donais, Shin-ichi Murase, Hannelore Asmussen and Alan F. Horwitz). - Ch. 20. Genes that control cell migration during mouse development (Carmen Birchmeier). - Index.