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Improving the quality of cancer clinical trials [electronic resource] : workshop summary / National Cancer Policy Forum, Margie Patlack and Sharyl Nass, rapporteurs.

Contributor(s): Patlak, Margie | Nass, Sharyl J | National Cancer Policy Forum (U.S.) | Institute of Medicine (U.S.) | ebrary, Inc.
Publisher: Washington, D.C. : National Academies Press, c2008Description: xii, 124 p. : ill. (some col.) ; 23 cm.Subject(s): Cancer -- Treatment -- United States | Clinical trialsGenre/Form: Electronic books. DDC classification: 362.196/994007 Online resources: An electronic book accessible through the World Wide Web; click to view Also available on the World Wide Web.
Contents:
Introduction -- New clinical trial designs. Phase 0 trials -- Adaptive trial designs -- Targeting multiple pathways with multiple drugs -- Preclinical model systems -- Molecular imaging. Current and developing methods -- Challenges of molecular imaging -- Screening for predictive markers. The challenges of clinical validation -- Bioimaging predictive markers -- Clinical translation -- Panel discussion -- Costs of clinical trials. Regulatory costs -- Patient accrual -- Global outsourcing -- Time is money -- Public-private collaborations -- Regulatory issues. Regulatory barriers to innovation -- Patient advocacy perspective -- Regulation of in vitro diagnostics -- Regulatory issues in improving cancer clinical trials -- Reports from the case study discussion groups. Adaptive trial design -- Phase 0 trials -- Imaging -- Use of proteomics/genomics to assign therapy in lung cancer -- Use of genetics/genomics to assign therapy.
Item type Current location Call number Status Date due Barcode
362.196/994007 (Browse shelf) Available

Includes bibliographical references.

Introduction -- New clinical trial designs. Phase 0 trials -- Adaptive trial designs -- Targeting multiple pathways with multiple drugs -- Preclinical model systems -- Molecular imaging. Current and developing methods -- Challenges of molecular imaging -- Screening for predictive markers. The challenges of clinical validation -- Bioimaging predictive markers -- Clinical translation -- Panel discussion -- Costs of clinical trials. Regulatory costs -- Patient accrual -- Global outsourcing -- Time is money -- Public-private collaborations -- Regulatory issues. Regulatory barriers to innovation -- Patient advocacy perspective -- Regulation of in vitro diagnostics -- Regulatory issues in improving cancer clinical trials -- Reports from the case study discussion groups. Adaptive trial design -- Phase 0 trials -- Imaging -- Use of proteomics/genomics to assign therapy in lung cancer -- Use of genetics/genomics to assign therapy.

TSLHHL

Also available on the World Wide Web.

Electronic reproduction. Palo Alto, Calif. : ebrary, 2009. Available via World Wide Web. Access may be limited to ebrary affiliated libraries.