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High-throughput screening in drug discovery / edited by Jörg Hüser.

Contributor(s): Hüser, Jörg [(ed.)].
Series: Methods and principles in medicinal chemistry ; v. 35. Publisher: Weinheim : Wiley-VCH, c2006Description: xviii, 343 p. : ill. (some col.) ; 25 cm.ISBN: 3527312838 (hbk.); 9783527312832 (hbk.).Subject(s): High throughput screening (Drug development)DDC classification: 615.19
Contents:
Preface. - List of contributors. - Pt. 1. Concept of screening. 1. Chemical genetics : use of high-throughput screening to identify small-molecule modulators of proteins involved in cellular pathways with the aim of uncovering protein function / Sa L. Chiang. - 2. High-throughput screening for targeted lead discovery / Jorg Huser, Emanuel Lohrmann, Bernd Kalthof, Nils Burkhardt, Ulf Bruggemeier, Martin Bechem. - 3. Tools and technologies that facilitate automated screening / John Comley. - 4. Functional cell-based assays for targeted lead discovery in high-throughput screening / Jorg Huser, Bernd Kalthof, Jochen Strayle. - 5. Biochemical assays for high-throughput screening / William D. Mallender, Michael Bembenek, Lawrence R. Dick, Michael Kuranda, Ping Li, Saurabh Menon, Eneida Pardo, Tom Parsons. - 6. Image-based high-content screening - a view from basic sciences / Peter Lipp, Lars Kaestner. - 7. Methods for statistical analysis, quality assurance and management of primary high-throughput screening data / Hanspeter Gubler. - 8. Chemoinformatic tools for high-throughput screening data analysis / Peter G. Nell, Stefan M. Mundt. - 9. Combinatorial chemistry and high-throughput screening / Roger A. Smith, Nils Griebenow. - 10. High-throughput screening and data analysis / Jeremy S. Caldwell, Jeff Janes. - Appendix. - Index.
Item type Current location Call number Copy number Status Notes Date due Barcode Remark
Main Collection TU External Storage-LCS
615.19 HIG (Browse shelf) 1 Available SBSxx,36200,03,GR 5000079876 Please fill up online form at https://taylorslibrary.taylors.edu.my/services/external_storage1

Includes bibliographical references and index

Preface. - List of contributors. - Pt. 1. Concept of screening. 1. Chemical genetics : use of high-throughput screening to identify small-molecule modulators of proteins involved in cellular pathways with the aim of uncovering protein function / Sa L. Chiang. - 2. High-throughput screening for targeted lead discovery / Jorg Huser, Emanuel Lohrmann, Bernd Kalthof, Nils Burkhardt, Ulf Bruggemeier, Martin Bechem. - 3. Tools and technologies that facilitate automated screening / John Comley. - 4. Functional cell-based assays for targeted lead discovery in high-throughput screening / Jorg Huser, Bernd Kalthof, Jochen Strayle. - 5. Biochemical assays for high-throughput screening / William D. Mallender, Michael Bembenek, Lawrence R. Dick, Michael Kuranda, Ping Li, Saurabh Menon, Eneida Pardo, Tom Parsons. - 6. Image-based high-content screening - a view from basic sciences / Peter Lipp, Lars Kaestner. - 7. Methods for statistical analysis, quality assurance and management of primary high-throughput screening data / Hanspeter Gubler. - 8. Chemoinformatic tools for high-throughput screening data analysis / Peter G. Nell, Stefan M. Mundt. - 9. Combinatorial chemistry and high-throughput screening / Roger A. Smith, Nils Griebenow. - 10. High-throughput screening and data analysis / Jeremy S. Caldwell, Jeff Janes. - Appendix. - Index.