Kenakin, Terrence P.

A pharmacology primer : theory, applications, and methods / Terry P. Kenakin. - 3rd ed. - Burlington : Elsevier/Academic Press, c2009. - xix, 389 p. : ill. (some col.) ; 29 cm.

Includes bibliographical references and index.

What is pharmacology? -- How different tissues process drug response -- Drug-receptor theory -- Pharmacological assay formats : binding -- Agonists : the measurement of affinity and efficacy in functional assays -- Orthosteric drug antagonism -- Allosteric drug antagonism -- The process of drug discovery -- Pharmacokinetics -- Target- and system-based strategies for drug discovery -- "Hit" to drug : lead optimization -- Statistics and experimental design -- Selected pharmacological methods -- Exercises in pharmacodynamics and pharmacokinetics.

9780123745859 (hbk.)


Pharmacology, Experimental.
Receptors, Drug--physiology.
Dose-Response Relationship, Drug.
Pharmacology--methods.

615.7 / KEN