TY - BOOK AU - Nassar,Ala F. TI - Biotransformation and metabolite elucidation of xenobiotics SN - 9780470504789 (hbk.) U1 - 615.9 PY - 2010/// CY - Hoboken, N.J. PB - John Wiley KW - Xenobiotics KW - Metabolism KW - Metabolites KW - Identification KW - Biotransformation (Metabolism) N1 - "Characterization and identification"--Cover; Includes bibliographical references and index; Human biotransformation / Andrew Parkinson -- Analytical tools and approaches for metabolite identification in drug metabolism / Yongmei Li -- Tools of choice for accelerating metabolite identification : mass spec technology drives metabolite identification studies forward / Ala Nassar -- Improving drug design : considerations for the structural modification process / Ala Nassar -- Case study : the unanticipated loss of N2 from novel dna alkylating agent laromustine by collision-induced dissociation : novel rearrangements / Ala Nassar, Tukiet T. Lam -- Case study : identification of in vitro metabolite/decomposition products of the novel DNA alkylating agent laromustine / Ala Nassar, TuKiet T. Lam -- Strategies for the detection of reactive intermediates in drug discovery and development / Mark P. Grillo -- Safety testing of drug metabolites : MIST guidance impact on the practice of industrial drug metabolism / J. Greg Slatter ER -