TY  - BOOK
AU  - Torrence,Paul F.
TI  - Antiviral drug discovery for emerging diseases and bioterrorism threats
SN  - 0471668273 (hbk.)
U1  - 616.91061 
PY  - 2005///
CY  - Hoboken, N.J.
PB  - Wiley-Interscience
KW  - Antiviral agents
KW  - Drug development
KW  - Bioterrorism
KW  - Antiviral Agents
KW  - therapeutic use
KW  - prevention & control
KW  - Communicable Diseases, Emerging
KW  - drug therapy
KW  - Drug Design
N1  - Includes bibliographical references and index; Preface. - Contributors. 1. Introduction: pestilence, plague, bioterrorism / Paul F. Torrence. - 2. Viral bioterrorism and antiviral countermeasures / M. Bray. - 3. Overview of antiviral drug discovery and development / C. Tseng. - 4. Antiviral drug targets and strategies for emerging viral diseases and bioterrorism threats / E. de Clercq . - 5. Perspectives for the therapy against arenavirus infections / E.B. Damonte, C.C. Garcia. - 6.  S-adenosylhomocysteine hydrolase inhibitors as a source of anti-filovirus agents / S.W. Schneller, M. Yang . - 7. Antiviral strategies for Ebola virus / R.N. Harty and J. M. Licata. - 8. IMPDH inhibitors : discovery of antiviral agents against emerging diseases / V. Nair. - 9. Lethal mutagenesis : exploiting error-prone replication of riboviruses for Antiviral therapy / J.D. Graci, C.E. Cameron. - 10. Structural biology of flavivral replications and opportunities for drug design / K. Murthy. - 11. Confronting new and old antiviral threats : broad spectrum potential of prenylation inhibitors / M. Elazar, J.S. Glenn. - 12. West Nile virus: New targets for petential antivirals. - 13. The emergence of pandemic influenza A : bioterrorist versus mother nature. - 14. The discovery and development of new antivirals for smallpox / E.R. Kern. - 15. Viral countermeasures to the host interferon response: role of the vaccinia virus E3L and K3L, genes. 16. Broad-spectrum antiviral prophylaxis: inhibition of viral infection by polymer grafting with methoxpoly (ethylene glycol). - 17. Viral evasion of the interferon system: novel targets for grug discovery/ Paul F. Torence and Linda Powell. - Index
ER  -