TY  - BOOK
AU  - Hüser,Jörg
TI  - High-throughput screening in drug discovery
SN  - 3527312838 (hbk.)
U1  - 615.19 
PY  - 2006///
CY  - Weinheim
PB  - Wiley-VCH
KW  - High throughput screening (Drug development)
N1  - Includes bibliographical references and index; Preface. - List of contributors. - Pt. 1. Concept of screening. 1. Chemical genetics : use of high-throughput screening to identify small-molecule modulators of proteins involved in cellular pathways with the aim of uncovering protein function / Sa L. Chiang. - 2. High-throughput screening for targeted lead discovery / Jorg Huser, Emanuel Lohrmann, Bernd Kalthof, Nils Burkhardt, Ulf Bruggemeier, Martin Bechem. - 3. Tools and technologies that facilitate automated screening / John Comley. - 4. Functional cell-based assays for targeted lead discovery in high-throughput screening / Jorg Huser, Bernd Kalthof, Jochen Strayle. - 5. Biochemical assays for high-throughput screening / William D. Mallender, Michael Bembenek, Lawrence R. Dick, Michael Kuranda, Ping Li, Saurabh Menon, Eneida Pardo, Tom Parsons. - 6. Image-based high-content screening - a view from basic sciences / Peter Lipp, Lars Kaestner. - 7. Methods for statistical analysis, quality assurance and management of primary high-throughput screening data / Hanspeter Gubler. - 8. Chemoinformatic tools for high-throughput screening data analysis / Peter G. Nell, Stefan M. Mundt. - 9. Combinatorial chemistry and high-throughput screening / Roger A. Smith, Nils Griebenow. - 10. High-throughput screening and data analysis / Jeremy S. Caldwell, Jeff Janes. - Appendix. - Index
ER  -