TY  - BOOK
AU  - Edler,Lutz
AU  - Kitsos,Christos Par
TI  - Recent advances in quantitative methods in cancer and human health risk assessment
SN  - 0470857560 (hbk.)
U1  - 616.994071 
PY  - 2005///
CY  - Chichester, England
PB  - J. Wiley
KW  - Cancer
KW  - Risk factors
KW  - Mathematical models
N1  - Contributors. - Preface. - Introduction. - I: Cancer and human health risk assessment. - 1. Principles of cancer risk assessment: The risk assessment paradigm. - II: Biological aspects of Carcinogenesis. -  2. Molecular epidemiology in cancer research. - 3. Genetic polymorphisms in metabolising enzymes as lung cancer risk factors.  - 4. Biological and mathematical aspects of multistage carcinogenesis . - 6. Risk assessment and chemical and radiation hormesis: A short commentary and bibliographic review. - III: Modeling for cancer risk assessment. - 7. Modeling exposure and target organ concentrations. - 8. Stochastic carcinogenesis models. - 9. A unified modeling approach: From exposure to disease endpoints. - 10. Modeling lung cancer screening. - 11. Optimal regimens of cancer screening. - IV: Statistical approaches for carcinogenesis studies. - 12. Analysis of survival data with non-proportional hazards and crossings of survival functions. - 13. Dose response modeling. - 14. Benchmark dose approach. - 15. Uncertainty analysis: the Bayesian approach. - 16. Optimal designs for bioassays in carcinogenesis. - V: Specific modeling approaches for health risk assessment. - 17. Cancer risk assessment for mixtures. - 18. Designs and models for mixtures: Assessing cumulative risk. - 19. Estimating the natural history of breast cancer from bivariate data on age and tumor size at diagnosis. - VI: Case studies. - 20. Statistical issues in search for biomarkers of colorectal cancer using microarray experiments. - 21. Optimal experimental designs for prediction of morbidity after lung resection. - 22. Logistic regression methods and their implementation. - 23. The use of logistic regression, discriminant analysis and classification trees to predict holding on remission in childhood leukemia. - 24. Non-melanoma skin and lung cancer incidence in relation to arsenic exposure: 20 years of observation. - 25.  Thyroid cancer incidence rates in Zaragoza. - References. - Index
ER  -