Human molecular genetics 2 /
Human molecular genetics two
Tom Strachan and Andrew P. Read
- 2nd ed.
- N.Y. : John Wiley & Sons (Asia), 1999
- xxiii, 576 p. : ill. ; 28 cm.
Published in Asia by arrangement with BIOS Scientific Publishers, Oxford, U.K.
Abbreviations. - Preface to the first edition. - Preface to the second edition. - Before we start - genetic data and the Internet. - Ch. 1. DNA structure and gene expression. - Ch. 2. Chromosomes in cells. - Ch. 3. Genes in pedigrees. - Ch. 4. Cell-based DNA cloning. - Ch. 5. Nucleic acid hybridization assays. - Ch. 6. PCR, DNA sequencing and in vitro mutagenesis. - Ch. 7. Organization of the human genome. - Ch. 8. Human gene expression. - Ch. 9. Instability of the human genome: mutation and DNA repair. - Ch. 10. Physical and transcript mapping. - Ch. 11. Genetic mapping of mendelian characters. - Ch. 12. Genetic mapping of complex characters. - Ch. 13. Genome projects. - Ch. 14. Our place in the tree of life. - Ch. 15. Identifying human disease genes. - Ch. 16. Molecular pathology. - Ch. 17. Genetic testing in individuals and populations. - Ch. 18. Cancer genetics. - Ch. 19. Complex diseases: theory and results. - Ch. 20. Studying human gene structure, expression and function using cultured cells and cell extracts. - Ch. 21. Genetic manipulation of animals. - Ch. 22. Gene therapy and other molecular genetic-based therapeutic approaches. - Glossary. - Indexes.