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Microfluidic applications in biology : from technologies to systems biology / edited by Niels Lion, Joel S. Rossier, and Hubert H. Girault.

Contributor(s): Publication details: Weinheim : Wiley-VCH, 2006Description: xviii, 340 p. : ill. (some col.) ; 25 cmISBN:
  • 3527317619 (hbk.)
  • 9783527317615 (hbk.)
Subject(s): DDC classification:
  • 629.8042 MIC
Contents:
On-line chemiluminescence detection for isoelectric focusing of heme proteins on microchips. - 2. A simple microfluids system for efficient capillary electrophoretic separation and sensitive fluorimetric detection of DNA fragments using light-emitting diode and liquid-core waveguide techniques. - 3. Determination of biochemical species on electrophoresis chips with an external contactless conductivity detector. - 4. In-channel indirect amperometric detection of nonelectroactive anions for electrophoresis on a poly(dimethyisiloxane) microchip. - 5. Coupling on-chip solid-phase extraction to electrispray mass spectrometry through an in integrated electrospray tip. - 6. Electrospray interfacing microfluidics to MALDI-MS. - 7. Nanoliquid chromatography-mass spectrometry of oligosaccharides employing graphitized carbon chromatography on microchip with a high-accuracy mass analyzer. - 8. Chip electrospray mass spectrometry for carbohydrate analysis. - 9. Utility of lab-on-a chip technology for high-throughput nucles acid and protein analysis. - 10. Analysis of amino acids and proteins using a polu(methyl methacrylate). - 11. Single cellmanipulation, analytics, and label-free protein detection in microfluidic devices for systems nanobiology. - 12. Fast immobilization of probe beads by dielectrophoresis-controlled adhesion in a versatile microfluidic platform for affinity assay. - 13. Droplet fusion by alternating current (AC) field electrocoalescence in microchannels. - 14. Microgluidic flow focusing: drop size and scaling in pressure versus flow-rate-diver pumping. - 15. Aligning fast alternating current electroosmotic flow fields and characteristic frequencies with dielectroporetic traps to achieve rapid bacteria detection. - 16. Dielectrophoresis induced clustering regimes of viable yeast cells. - 17. 3-d electrode designs for flow-through dielectrophoretic systems. - 18. Parallel mixing of photolithographically defined nanoliter volumes using elastomeric microvalve arrays. - 19. Method development and measurements of endogenous serine/threonine akt phosphorylation using capillary electrophoresis for systems biology. - 20. Comparison of a pump-around a diffusion-driven, and a shear-driven system for the hybridization of mouse lung and testis total RNA on microarrays. - 21. Microfluidic devicesfor the analysis of apoptosis. - 22. Effect of iron restriction on outer membrane protein composition of pseudomonas strains studies by conventional and microchip electrophoresis. - Index.
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Collection of articles published previously in the journal "Electrophoresis"

Includes bibliographical references and index

On-line chemiluminescence detection for isoelectric focusing of heme proteins on microchips. - 2. A simple microfluids system for efficient capillary electrophoretic separation and sensitive fluorimetric detection of DNA fragments using light-emitting diode and liquid-core waveguide techniques. - 3. Determination of biochemical species on electrophoresis chips with an external contactless conductivity detector. - 4. In-channel indirect amperometric detection of nonelectroactive anions for electrophoresis on a poly(dimethyisiloxane) microchip. - 5. Coupling on-chip solid-phase extraction to electrispray mass spectrometry through an in integrated electrospray tip. - 6. Electrospray interfacing microfluidics to MALDI-MS. - 7. Nanoliquid chromatography-mass spectrometry of oligosaccharides employing graphitized carbon chromatography on microchip with a high-accuracy mass analyzer. - 8. Chip electrospray mass spectrometry for carbohydrate analysis. - 9. Utility of lab-on-a chip technology for high-throughput nucles acid and protein analysis. - 10. Analysis of amino acids and proteins using a polu(methyl methacrylate). - 11. Single cellmanipulation, analytics, and label-free protein detection in microfluidic devices for systems nanobiology. - 12. Fast immobilization of probe beads by dielectrophoresis-controlled adhesion in a versatile microfluidic platform for affinity assay. - 13. Droplet fusion by alternating current (AC) field electrocoalescence in microchannels. - 14. Microgluidic flow focusing: drop size and scaling in pressure versus flow-rate-diver pumping. - 15. Aligning fast alternating current electroosmotic flow fields and characteristic frequencies with dielectroporetic traps to achieve rapid bacteria detection. - 16. Dielectrophoresis induced clustering regimes of viable yeast cells. - 17. 3-d electrode designs for flow-through dielectrophoretic systems. - 18. Parallel mixing of photolithographically defined nanoliter volumes using elastomeric microvalve arrays. - 19. Method development and measurements of endogenous serine/threonine akt phosphorylation using capillary electrophoresis for systems biology. - 20. Comparison of a pump-around a diffusion-driven, and a shear-driven system for the hybridization of mouse lung and testis total RNA on microarrays. - 21. Microfluidic devicesfor the analysis of apoptosis. - 22. Effect of iron restriction on outer membrane protein composition of pseudomonas strains studies by conventional and microchip electrophoresis. - Index.