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008 110218s2007 njua b 001 0 eng
020 _a9780471752158 (hbk.)
020 _a0471752150 (hbk.)
039 9 _a201103141636
_bwilmina
_c201103091409
_dmasrina
_c201102181401
_dVLOAD
_y201011291635
_zmuhammad_fadzli
082 0 4 _a615.19
_bART 2007
245 0 4 _aThe art of drug synthesis /
_cedited by Douglas S. Johnson, Jie Jack Li.
260 _aHoboken, N.J. :
_bWiley-Interscience,
_cc2007.
300 _axv, 276 p. :
_bill. ;
_c26 cm.
504 _aIncludes bibliographical references and index.
505 0 _aThe role of medicinal chemistry in drug discovery / John A. Lowe III -- Process research: how much? how soon? / Neal G. Anderson -- Aromatase inhibitors for breast cancer : exemestane (Aromasin), anastrozole (Arimidex), and letrozole (Femara) / Jie Jack Li -- Quinolone antibiotics : levofloxacin (Levaquin), moxifloxacin (Avelox), gemifloxacin (Factive), and garenoxacin (T-3811) / Chris Limberakis -- Triazole antifungals : itraconazole (Sporanox), fluconazole (Diflucan), voriconazole (Vfend), and fosfluconazole (Prodif) / Andrew S. Bell -- Non-nucleoside HIV reverse transcriptase inhibitors / Arthur Harms -- Neuraminidase inhibitors for influenza : oseltamivir phosphate (Tamiflu) and zanamivir (Relenza) / Douglas S. Johnson and Jie Jack Li -- Peroxisome proliferator-activated receptor (PPAR) agonists for type 2 diabetes / Jin Li -- Angiotensin AT1 antagonists for hypertension / Larry Yet -- Leading ACE inhibitors for hypertension / Victor J. Cee and Edward J. Olhava -- Dihydropyridine calcium channel blockers for hypertension / Daniel P. Christen -- Second-generation HMG-CoA reductase inhibitors / Jeffrey A. Pfefferkorn -- Cholesterol absorption inhibitors: ezetimibe (zetia) / Stuart B. Rosenblum -- Dual selective serotonin and norepinephrine reuptake inhibitors (SSNRIs) for depression / Marta Piñeiro-Núñez -- GABA receptor agonists for insomnia : zolpidem (Ambien), zaleplon (Sonata), eszopiclone (Estorra, Lunesta), and indiplon / Peter R. Guzzo -- Ligands: neurontin (Gabapentin) and lyrica (Pregabalin) / Po-Wai Yuen -- Approved treatments for attention deficit hyperactivity disorder : amphetamine (Adderall), methylphenidate (Ritalin), and atomoxetine (Straterra) / David L. Gray.
650 0 _aDrugs
_xDesign.
_921816
650 0 _aPharmaceutical chemistry.
_921185
700 1 _aJohnson, Douglas S.
_q(Douglas Scott),
_d1968-
_948894
700 1 _aLi, Jie Jack.
_921503
920 _aSMN : 156177
999 _c133926
_d133926